Sensoril is a patented extract of both the root and leaf of the Ashwagandha plant. A traditional herb with an ancient history, experts classify "The King of Ayurveda" as an adaptogen, a natural substance considered to help the body adapt to stress and normalize bodily processes. Ashwagandha is not typically thought of as a nootropic because it has so many documented effects on other body systems. It has positive effects on supporting healthy systemic inflammation, sleep quality, cortisol levels, cholesterol, blood pressure, physical power output, and the immune system, along with an extensive list of other effects. As a nootropic, ashwagandha supplementation impacts the GABA and serotonin neurotransmitters. It is commonly used to reduce stress and fatigue, as well as to improve mood and motivation.
Sensoril® is a patented, full-spectrum standardized root and leaf extract of Ashwagandha, or Withania Somnifera, a popular herb in Auyervedic medicine that has been used for centuries. Because of its long history and numerous applications, Ashwagandha is commonly referred to by practitioners as the King of Ayurveda.
Ashwagandha translates from Sanskrit as “smell of horse” referring to the distinctly horsey, farmhouse odor, and according to folklore it is thought eating the herb delivers the strength and vitality of a horse (5).
Ashwagandha is considered an adaptogen, a substance that helps the body adapt to anxiety and stress on both physiological and psychological levels (7). Today, ashwagandha is mainly known for its positive effects on helping the body cope with stress, increase endurance, and enhance cognitive function, which seems to be a result of the herbs effect on stress and anxiety. (6). Ashwagandha has been shown to alleviate insomnia and effects from stress-related depression (8). It can directly reduce levels of the stress hormone, cortisol, leading to reductions in the immunosuppressive effects of stress (9). As a cognitive enhancing supplement, ashwagandha may be effective in treating Alzheimer’s disease as well as improving new memory formation (10).
Also, Ayurveda uses Ashwagandha to treat tumors and ulcers (3), to enhance virility, as an aphrodisiac, as a rejuvenating agent, to treat inflammation, fatigue, stress, diabetes, cardiovascular disease, and other illnesses (4). Outside of Ayurveda, it is thought to confer neuroprotective benefits (2). The herb also has some interesting implications as an anti-cancer treatment, and new research suggests it may serve as an effective adjuvant therapy used alongside other primary forms of cancer treatment (11).
Ashwagandha contains many biologically active compounds including polyphenols, antioxidants, and other molecules that act upon different mechanisms and enzymatic pathways in the body (12). Ashwagandha supports mechanisms that suppress metastasis and angiogenesis, it acts upon various neuroprotective and neurotransmission pathways in the brain such as the cholinergic system, dopaminergic, and glutaminergic system, and it interacts with proteins and enzymes involved in reducing inflammation and maintaining cellular integrity (13, 14, 15, 16). Though we know many of the pathways ashwagandha acts upon, many have yet to be elucidated by scientific investigation.
Clinical studies have shown Sensoril to reduce circulating levels of cortisol and C-Reactive Protein, and important marker for systemic inflammation. It has also demonstrated lower pulse rates and blood pressure compared to a placebo, as well as increases in DHEA (an important hormone related to memory and mood) and hemoglobin. Compared to control groups, subjects have reported fewer headaches, less fatigue, muscle pain, sleeplessness, forgetfulness, and irritability, along with improved appetite and concentration. In all the research, there are no reports of adverse side effects. The clinical dose of Sensoril to achieve these results is 125mg.
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